This research paper aims at examining the concept of sustainability in the Ghanaian construction industry with the objective of identifying possible barriers to sustainable construction in the Ghanaian construction industry. Consequently, research data was collected through a questionnaire survey of randomly selected professionals in the construction industry in Ghana. Data collected was mainly analyzed using Relative Importance Index to rank barriers identified. The results show that key barriers to sustainable construction are lack of demand for sustainable buildings, lack of strategy to promote sustainable construction, higher initial cost, lack of public awareness and lack of government support.