Portals are Web-based applications that give users a centralized point of access for information and applications of relevance. Therefore the portal paradigm is an attractive proposition for healthcare because it offers a solution to rapidly aggregate heterogeneous applications and services while offering a high level of customization and personalization to the users, patients, care givers and IT personnel. In this paper, we explain the motivations that led us to integrate a portal framework on top of our solution stack to create healthcare solutions for our partners and customers. We describe the challenges associated with this type of infrastructure for healthcare applications including security and context management. We present concrete solutions for specific portal applications integrating EHR, PHR, care and disease management functionalities.