Deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) is a novel therapy for neuropsychiatric disorders. Hypomania is a known complication of VC/VS DBS, but who is at risk is less understood. Factors such as family history, combined with details of DBS programming, might quantify that risk. The authors performed an iterative modeling procedure on a VC/VS DBS patient registry to identify key predictors. Hypomania was less common for men and for patients stimulated on the ventral right contact. It was more common with right monopolar stimulation. These findings may help to establish decision rules to reduce complications of VC/VS DBS.
Examined effect of long wait-time (≥8 weeks) for surgical treatment on survival of women with early-stage cervical cancer.• Long surgery wait-time was not associated with short-term disease recurrence of women with early-stage cervical cancer.• Systematic review suggests that surgery wait-time for up to 8 weeks may have limited/modest effect on disease recurrence.
Cesarean radical hysterectomy (cesarean-RH) is performed at the time of cesarean delivery for pregnant women with early-stage cervical cancer. 1 Cesarean-RH is a rare procedure and has been understudied; population statistics are lacking in the literature. This study examined the characteristics and perioperative outcomes of women with cervical cancer who underwent cesarean-RH. STUDY DESIGN: This is a population-based retrospective study that queried the Healthcare Cost and Utilization Project's National Inpatient Sample from 2007e2015. 2 The study start period of 2007 was chosen because of the distinction detailed surgical approaches for RH (abdominal vs other approaches). The study end period of 2015 was chosen because of the change in the International Classification of Disease coding schema. Cervical cancer cases that had both cesarean delivery and abdominal RH (cesarean-RH group) were compared with cases that had RH alone via laparotomy (open-RH; Supplemental Table). Characteristics associated with cesarean-RH and those associated with perioperative complications during the index admission for RH were assessed by fitting binary logistic regression models (conditional backward) in multivariable analyses. All analyses were based on the weighted model. 2
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