An efficient synthesis of imidazo[2,1-b][1,3]benzothiazoles and 9H-imidazo[1,2-a][1,3]benzimidazoles is described from a novel multicomponent reaction between 2-aminobenzothiazoles or 2-aminobenzimidazole, benzaldehydes, and imidazoline-2,4,5-trione under solvent-free conditions.
Benzimidazole derivatives R 0200 Efficient Synthesis of Imidazo[2,1-b][1,3]benzothiazoles and 9H-Imidazo[1,2-a][1,3]benzimidazoles under Solvent-Free Conditions. -A simple one-pot three-component reaction allows the synthesis of target compounds of potential synthetic and pharmacological interest. -(ADIB*, M.; SHEIBANI, E.; ZHU, L.-G.; BIJANZADEH, H. R.; Synlett 2008, 19, 2941-2944; Sch. Chem., Coll. Sci., Univ. Tehran, Tehran, Iran; Eng.) -Mais 14-127
Fused pyridine derivatives R 0450 An Efficient Synthesis of 3-Amino-2-arylimidazo[1,2-a]pyridines. -A one-pot reaction of 2-aminopyridines, aromatic aldehydes and imidazoline-2,4,5-trione provides the biologically interesting title compounds (IV) in excellent yields. -(ADIB*, M.; SHEIBANI, E.; ZHU, L.-G.; MIRZAEI, P.; Tetrahedron Lett. 49 (2008) 34, 5108-5110; Sch. Chem., Coll. Sci., Univ. Tehran, Tehran, Iran; Eng.) -Mais 48-145
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