The present study aims to examine the genetic variation of the ATP1B1 gene concerning hypertension and chronic kidney disease CKD. (120 ) blood samples from participants were obtained and divided into three groups: a first group representing hypertensive patients (hyper), a second group representing Hypertensive CKD  patients (hyper with CKD), and a third group representing a control group.   DNA was extracted from all blood samples and then converted to cDNA and the ARMS-PCR technique was used to investigate the single nucleotide polymorphism (SNP) from the ATP1B1, genes. The result of this study investigated that SNP rs2901029 located in ATP1B1 is significant association with hypertension and CKD.

The present study aims to examine the genetic variation of the  Aquaporin-2 gene concerning hypertension and chronic kidney disease CKD. (120 ) blood samples from participants were obtained and divided into three groups: a first group representing hypertensive patients (hyper), a second group representing Hypertensive CKD  patients (hyper with CKD), and a third group representing a control group.   DNA was extracted from all blood samples and then converted to cDNA and the ARMS-PCR technique was used to investigate the single nucleotide polymorphism (SNP) from the AQP-2, genes. The result of this study investigated that SNP rs3759126 located in AQP-2 is a significant association with hypertension and CKD.