A 65-year-old man who, when young, had had tuberculosis treated by therapeutic pneumothorax, consulted his family physician for a constitutional syndrome and dyspnea. At this time radiologic studies showed left pleural effusion with bilateral calcified plaques, an infiltrate in the upper left lobe, and a picture compatible with aspergilloma, all suggesting semi-invasive aspergillosis. The patient failed to show up for his followup visit, so no therapy could be started or further diagnostic tests ordered. One month later he was admitted to this hospital for a bronchopleural fistula (empyema necessitatis) with subsequent spontaneous hydropneumothorax and costal bone involvement. The patient underwent surgery because of his rapid worsening condition. Biopsy examination revealed a large pleural aspergilloma. Despite immediate antifungal therapy, the patient died. We believe this to be the first report of pleural Aspergillus with a bronchopleurocutaneous fistula and costal bone destruction.
El Trastorno del Espectro Autista (TEA) es un trastorno del neurodesarrollo que afecta al desarrollo social y de la comunicación, así como patrones de conductas restrictivas y repetitivas. El TEA también se asocia a una alta prevalencia de trastornos psiquiátricos coexistentes. En el esfuerzo de identificar características del ambiente familiar que puedan influir en el curso de estos trastornos coexistentes en individuos con TEA, los investigadores están explorando el constructo de Emociones Expresadas (EE) que mide la relación afectiva entre dos personas, cuyos dominios son el criticismo, calidez, relación y sobre-implicación emocional. El estudio actual tiene como objetivo revisar el constructo de EE, cómo se mide y se aplica en la relación paterno-filial en niños con desarrollo típico y población TEA y describir la adaptación cultural en español así como validar la traducción del contenido del Manual de Autism-Specify Five Minutes Sample Speech (ASFMSS).
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