The Zywave wavefront sensor with the fixating target turned off using the study settings and light conditions provided measurements of scotopic pupil diameter that were closest to the reference values (Procyon). With the other devices (Colvard pupillometer, Zywave aberrometer with the fixating target switched on, Wasca aberrometer, and Orbscan topographer), the difference was statistically significant.
We feel that using the largest recorded pupil size rather than the mean of the 3 may provide a better representation of the scotopic pupil. After all, it is the largest natural pupil size we are interested in and this is this pupil size that one should cover in planning for refractive surgery to avoid side effects such as glare.
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