Introduction:The antimicrobial, antioxidant and cytotoxicity activities of the ethanolic and aqueous extracts of Targets multiflora Kunth were evaluated, which were collected in the province of Yauyos department of Lima-Perú. The antimicrobial activity was evaluated by the well diffusion method on agar against Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 8739, Method: Pseudomonas aeruginosa ATCC 9027, Bacillus subtilis ATCC 6633, Candida albicans ATCC 14053 and Aspergillus niger ATCC 16404. Antioxidant activity evaluated by the DPPH method and the cytotoxic activity was evaluated by the bioassay of cytotoxicity in Artemia salina (CYTED). In the ethanolic extract, halos were formed against Escherichia coli (11.33 mm + 0.58), Pseudomonas aeruginosa (13 mm + 1.0) and Staphyloccocus aureus (15.67 mm + 1.15) strains; and the aqueous extract against the Aspergillus niger strain (13.67 mm + 0.58). Results:The Ethanolic extract showed an IC 50 of 60.93 μg/mL + 0.40; and the aqueous extract 40.42 μg/mL + 0.24. The Ethanolic extract showed a LC 50 of 35.568 μg/mL and the aqueous extract 386.048 μg/mL. Conclusion:The Ethanolic extract showed antimicrobial activity (against Escherichia coli, Pseudomonas aeruginosa and Staphyloccocus aureus), antioxidant activity and high cytotoxic activity; while the aqueous extract presented antimicrobial activity (against Aspergillus niger), antioxidant activity and moderate cytotoxic activity.

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Parkinson's disease is a genetically heterogeneous, idiopathic and metacentric neurodegenerative disease of the nervous system characterized by progressive generalized slowing movements like bradykinesia, weakness, tremor, and rigidity, and postural instability in along with Parkinson's disease has been pondered to be a non-genetic distemper. A different way, features are associated such as sleep dysfunction, loss of smell, mood disorder, constipation, excessive salivation, and excessive periodic limb movements in sleep. Feudatory factors encompass head injury, pesticide exposure, and agriculture background. Results with development and assembling of αsynuclein in the central nervous system in the substantia nigra. A little while back, in North American, Parkinson's disease is a significant relationship indicated to 39.5cM of chromosome 2 (2q36-37; PARK11) portion on the deep arm. Immune-related disorder, notably Crohn's and leprosy diseases are also associated with Parkinson's disease, however around 15% persona with Parkinson's disease have primary level correlative who has the distemper in the genes including LRRK2, SNCA, last one GBA found as a keek part for sporadic Parkinson's disease.