Evan R. Himes scite author profile

Highlights Specific knockout of Stat3 in osteocytes suppresses loading induced bone formation. Stat3 deficiency in osteocytes decreases the material properties of femur. Stat3 inhibitor causes Reactive Oxidative Species (ROS) accumulation in MLO-Y4 osteocytes. Stat3 inhibitor blocked ATP-induced intracellular calcium influx into MLO-Y4 osteocytes.

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Evan R. Himes

Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function

Deletion of Nrf2 reduces skeletal mechanical properties and decreases load-driven bone formation

Stat3 in osteocytes mediates osteogenic response to loading

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