Evgeny Berdyshev scite author profile

Background: New pharmacological entities are actively sought for treatment of inherited and age-related retinal degenerative diseases. Results: Sulfaphenazole, a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme, was identified as a novel cytoprotective agent against light-induced death of photoreceptors. Conclusion: Cytochrome P450 CYP2C epoxygenases mediate photochemical stress-induced death of photoreceptors. Significance: The CYP monooxygenase system is a risk factor for retinal photodamage.

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P173 - Rôle du métabolisme des céramides dans l’apoptose des cellules bêta-pancréatiques induite par le palmitate

Coant¹,

Véret²,

Berdyshev³

et al. 2011

Diabetes & Metabolism

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Evgeny Berdyshev

CFTR Regulation of Intracellular pH and Ceramides Is Required for Lung Endothelial Cell Apoptosis

Cytochrome P450 2C Epoxygenases Mediate Photochemical Stress-induced Death of Photoreceptors

P173 - Rôle du métabolisme des céramides dans l’apoptose des cellules bêta-pancréatiques induite par le palmitate

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