The article is devoted to the issue of formation of indicators intended for the assessment by textile organizations of their economic security as a key condition for the functioning and development prospects of all organizations, including this national economic sector, which is a set of universal directions of the national economy of a mass nature, without which the life of people in professional and domestic life is impossible, requiring knowledge and application of indicators to assess its real level, serving as a yardstick in taking appropriate anti-crisis measures. The study is based on the final and intermediate desired benchmarks (goals and objectives). The goal is to offer and justify the formed system of indicators of the economic security of textile organizations, based on the author's position, focused on the effectiveness and cost (direct and indirect profitability) of economic processes and justified by commodity-money relations interacting with market laws inherent in the modern era, in which they carry out their activities along with other economic entities. The objectives of the study to achieve it are the study of sectoral economic cycles and other elements of productive forces in the textile industry correlated with them, the choice and application of methods and techniques (computationalconstructive and inductive methods) in the formation of this system of indicators. Using such knowledge, a system of general and particular indicators of the effectiveness and cost of the activities of textile organizations has been built, and their formalized relationship is shown, which allows them to quickly identify reserves for optimizing financial benefits. The provided material can be useful for persons engaged in theoretical and applied developments in the field of ensuring the economic security of organizations in the textile industry and other industries in terms of a general methodological approach based on uniform scientific principles.