The low productivity of cucumber plants in Indonesia can be caused by several factors, one of which is fertilization. Fertilization on Inceptisol soil which has a low nitrogen content is needed to increase cucumber crop yields. The use of inorganic fertilizers is limited to avoid environmental pollution, so the use of biofertilizers can be an environmentally friendly option. The purpose of this study was to determine the effect of concentration and interval application of azolla extract based biofertilizer on the total soil N, plant N content, Azotobacter population and cucumber yield. The experiment was carried out from August to November 2021 at the Ciparanje Experimental Garden, Faculty of Agriculture, Padjadjaran University. This experiment used a Completely Randomized Block Design of a combination concentrations (0, 5, 10, 15, 20 mL.L-1) and time of application (1, 2, 3 times). The results showed that the application of azolla extract based biofertilizer with different concentrations and application times had a significant effect on the azotobacter population but had no significant effect on soil nitrogen levels, plant nitrogen concentrations, and cucumber yields. The addition of 20 mL/L 2 times application of azolla-based biofertilizer increased cucumber fruit weight by 35.97% compared to control but did not cause a significant increase in yield

Background: Sympathetic hyperactivity is one of the several factors that influence left ventricular dyssynchrony post anthracycline. Cardiovascular risk factors affect the acceleration of left ventricular dyssynchrony. The purpose of this study is to assess the difference in correlation coefficient between HRV and mechanical dispersion in breast cancer patients with and without cardiovascular risk factors after anthracycline administration.Method: This was a cross sectional study with linear regression analysis conducted at Hasan Sadikin General Hospital Bandung between July-October 2018. Subjects were breast cancer patients who had received 6 cycles of FAS and were divided into 2 groups. Group I was patients with breast cancer who have cardiovascular risk factors and group II was without cardiovascular risk factors. Sympathetic hyperactivity was assessed using HRV baseline frequency with minimum duration of recording and left ventricular dyssynchrony was assessed using MD method by echocardiography.Result: This study involved 66 patients. Group I (n=34, age 50.3±6.3 years) and group II (n=32, age 48.5±9 years). The median of LF/HF ratio was 2.7 ms2 (group I) and 1.9 ms2 (group II). MD value in group I and group II was 52.2±13.6 ms and 45.7±8.8 ms, respectively. The result of linear regression analysis showed positive correlation between the LF/HF ratio and MD in group I (r=0.546, p=0.001) and group II (r=0.423, p=0.016) after adjusting three confounding factors (systolic blood pressure, cumulative dose of Doxorubicin, and age).Conclusion: Correlation coefficient of HRV with mechanical dispersion in post anthracycline breast cancer patients in those with cardiovascular risk factorswas worse compared to those without cardiovascular risk factors but was not statistically significant.

The application of Azolla-based liquid biofertilizer is a fertilizer supplement for vegetable crops that utilizes the natural potential around agricultural land. Various studies reveal that the concentration of liquid biofertilizer application varies so that for the efficient use of liquid biofertilizer it is necessary to find the right concentration. The purpose of this study was to analyze the response of pakcoy plants through the application of different concentrations of biofertilizers to increase the growth and yield of pakcoy plants. This study used seven treatments with six replications arranged according to a randomized block design. The experimental treatments consisted of: without giving biofertilizers (K0), 5 ml l -1 biofertilizers (K1), 10 ml l -1 biofertilizers (K2), 15 ml l -1 biolofertilizers (K3), 20 ml l -1 biofertilizers (K4), 25 ml l -1 biofertilizer (K5), 30 ml l -1 biofertilizer (K6). The results showed that concentrations of biofertilizers ranging from 5 to 30 ml/l could increase plant height, number of leaves, leaf width, leaf length, and leaf area and fresh weight of pakcoy plants compared to no application of biofertilizers. The concentration of 10 ml l -1 biofertilizer resulted in a higher number of pakcoy leaves than the control but did not differ from the fresh weight of the pakcoy plant at each concentration of biofertilizer given. The application of biofertilizer with a concentration of 10 ml l -1 increased the fresh weight of pakcoy plants twice or 100.74% compared to the control. Azolla-based liquid biolofertilizers can be used as additional nutrients for NPK fertilizers to increase the growth and yield of pakcoy plants.