SummaryBackgroundGlobal inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia.MethodsCancer registries participating in CONCORD were asked to submit tumour registrations for all children aged 0–14 years who were diagnosed with leukaemia between Jan 1, 1995, and Dec 31, 2009, and followed up until Dec 31, 2009. Haematological malignancies were defined by morphology codes in the International Classification of Diseases for Oncology, third revision. We excluded data from registries from which the data were judged to be less reliable, or included only lymphomas, and data from countries in which data for fewer than ten children were available for analysis. We also excluded records because of a missing date of birth, diagnosis, or last known vital status. We estimated 5-year net survival (ie, the probability of surviving at least 5 years after diagnosis, after controlling for deaths from other causes [background mortality]) for children by calendar period of diagnosis (1995–99, 2000–04, and 2005–09), sex, and age at diagnosis (<1, 1–4, 5–9, and 10–14 years, inclusive) using appropriate life tables. We estimated age-standardised net survival for international comparison of survival trends for precursor-cell acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML).FindingsWe analysed data from 89 828 children from 198 registries in 53 countries. During 1995–99, 5-year age-standardised net survival for all lymphoid leukaemias combined ranged from 10·6% (95% CI 3·1–18·2) in the Chinese registries to 86·8% (81·6–92·0) in Austria. International differences in 5-year survival for childhood leukaemia were still large as recently as 2005–09, when age-standardised survival for lymphoid leukaemias ranged from 52·4% (95% CI 42·8–61·9) in Cali, Colombia, to 91·6% (89·5–93·6) in the German registries, and for AML ranged from 33·3% (18·9–47·7) in Bulgaria to 78·2% (72·0–84·3) in German registries. Survival from precursor-cell ALL was very close to that of all lymphoid leukaemias combined, with similar variation. In most countries, survival from AML improved more than survival from ALL between 2000–04 and 2005–09. Survival for each type of leukaemia varied markedly with age: survival was highest for children aged 1–4 and 5–9 years, and lowest for infants (younger than 1 year). There was no systematic difference in survival between boys and girls.InterpretationGlobal inequalities in survival from childhood leukaemia have narrowed with time but remain very wide for both ALL and AML. These results provide useful information for health policy makers on the effectiveness of health-care systems and for cancer policy makers to reduce inequalities in childhood cancer survival.FundingCanadian Partnership Against Cancer, Cancer Focus Northern Ireland, Cancer In...

The distribution of ovarian cancer histology varies widely worldwide. Type I epithelial, germ cell and sex cord-stromal tumours are generally associated with higher survival than type II tumours, so the proportion of these tumours may influence survival estimates for all ovarian cancers combined. The distribution of histological groups should be considered when comparing survival between countries and regions.

Background: In Indonesia, the incidence of colorectal cancer was separated in colon and rectum cancer. The incidence of rectum cancer ranked number five in male and number eight in female. The incidence of colon cancer ranked number seven in male and number nine in female. Aim: The aim of this study is to know the profile of colorectal cancer in Indonesia. Methods: Using data collected from population based cancer registry in 14 provinces (26 cities/districts) in Indonesia which was developed into a site specific cancer registry. All of the data diagnosed from 2008-2012. The classification of cases is used WHO criteria, ICD-O-3 (C18-C20). There were 3453 patients included in this study. CanReg5 was used as the software for entry and analyze the data. All primary health care and hospitals sent the data to the 14 National Referral Hospitals which located in each provinces. Finally, the 14 National Referral Hospitals sent the data to Dharmais National Cancer Center. Results: Incidence of colorectal cancer was higher in male (54%) than female (46%). Peak cancer cases occurred in the age of 50-54 years. DKI Jakarta, Central Java, DIY Yogyakarta as the three provinces which have highest incidence for colorectal cancer. The highest microscopic verification was in Papua, Central Java, and South Sulawesi. The highest percentage location was in the colon. The type of morphology was adenocarcinoma. Conclusion: The incidence of colon cancer entered in the top ten most common cancers in Indonesia. The quality of data still needed to be improved.

Latar belakang: Kanker paru adalah kanker yang paling sering ditemukan. Pada tingkat populasi, kejadian dan kematian akibat kanker paru menempati urutan pertama dari seluruh kasus kanker yang terjadi pada laki-laki dan kanker tersering keempat pada perempuan, sementara kesintasan kanker paru adalah sangat singkat yaitu 13 bulan. Penelitian ini menggambarkan beberapa variabel kasus kanker paru di Rumah Sakit Kanker Dharmais (RSKD) secara epidemiologi dan klinis. Metode: Penelitian dilakukan secara potong lintang dengan mengambil data kanker paru tahun kejadian 2008-2012 di RSKD dengan sumber data registrasi kanker berbasis rumah sakit. Hasil: Kasus kanker paru pada laki-laki tiga kali lebih sering terjadi jika dibanding pada perempuan dan kasus mulai meningkat di kelompok usia 45 tahun. Letak kanker lebih sering ditemukan pada paru kanan (48,2%) dan adenokarsinoma merupakan jenis yang paling sering ditemukan (41,7%). Sebanyak 60,1% pasien tidak diketahui stage kanker yang diderita pada saat pertama kali kunjungan dan tulang merupakan lokasi metastasis yang paling sering ditemukan (36,4%). Kesimpulan: letak kanker paru pada pru kanan, jenis adenokarsinoma, stage belum diketahui saat pertama kali kunjungan dan metastasis ke tulang merupakan gambaran epidemiologi dan klinis pasien kanker paru di RSKD yang paling sering ditemukan.

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