Leiomyomatosis peritonealis disseminata (LPD) is a very rare disease characterized by formation of multiple smooth muscle tumor or nodules disseminated throughout the omental and peritoneal surfaces. It is a benign disease of unknown etiology which usually occur in women of reproductive age. The tumor may originate from the mesentery, the omentum and even the peritoneum covering the abdominal wall. Literatures have shown the association between LPD and endometriosis. Some believed the tumors arise from endometriosis foci, though no evidence to support that. The presentations are nonspecific and vague. Diagnosis is a challenge and histopathological examination (HPE) is required to diagnose LPD. Surgery is the mainstay of treatment. Prognosis is good even literatures shown that recurrence is possible after tumor resection.