Colonisation with Helicobacter pylori may influence susceptibility to gastroduodenal injury and ulceration in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to determine if Helicobacter pylori colonisation altered eicosanoid synthesis by gastric musoca in these patients. Sixty five patients with longstanding NSAID intake and 23 control subjects underwent endoscopy.
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