Objectives: To evaluate the impact of innovative teaching programme on knowledge and skill regarding basic cardiac life support. 2 Method: quasi-experimental research design with a quantitative research approach was undertaken on 30 students . Results: The findings revealed that innovative teaching programme on knowledge and skill regarding basic cardiac life support was effective as the mean was 3.87 with standard deviation of 2.11 in pretest but in the post test the mean was 15.73 with standard deviation of 1.01 which was found statistically highly significant at p<0.001 level. Conclusion: That innovative teaching programme was found highly significant in enhancing the knowledge and skills of students on basic life support measures. 3