На сегодняшний день существует два принципиально разных хирургических доступа для оперативного лечения пациентов с кистами верхнечелюстной пазухи: экстраназальный (через трепанационное отверстие в передней стенке верхнечелюстной пазухи) и эндоназальный. Экстраназальный подход обеспечивает хороший обзор операци-онного поля, позволяет надежно удалить кисту из всех отделов синуса, однако сопровождается травмированием мягких тканей лица и болевыми ощущениями в проекции вмешательства в послеоперационном периоде. С появлением эндоскопической техники хирурги стали удалять кисты через естественное соустье верхнечелюстной пазухи в области среднего носового хода. Данная методика позволяет избежать травмирования передней стенки пазухи,

The article presents a case of the middle ear obliteration in a 45 years old female patient that complained of a long-term continuous otorrhea and underwent 4 surgeries for congenital middle ear development abnormality (microtia, external auditory canal (EAC) atresia), paraauricular fistula and stage 3 chronic sensoneural hearing loss. The work provides detailed description of the course of interference that resulted in the fact, that no complaints of the operated ear have been observed for 12 months. Therefore, the fat tissue obliteration of tympanic cavity may be used as the method of choice in case of treatment of post-surgical cavity without result in patients with the chronic suppurative otitis media in the cases where reconstructive hearing improvement surgery is impossible or is not indicated. The latter is observed in the patients with the expressed sensoneural hearing loss.

Most of the standard methods of treatment of patients with inflammatory nose and paranasal sinuses diseases are not effective enough. Argogel is a topical nanotechnology-based preparation which could be a conservative therapeutic alternative for such patients. The objective of this study was to evaluate the efficacy of topical application of the preparation containing silver nanoparticles in the early post-surgery period of the nasal cavity and paranasal sinuses. The study covered 40 patients with chronic rhinosinusitis aged from 25 to 70 after the ambilateral endoscopic maxillary ethmoidotomy. In the course of treatment on most of the patients, Argogel preparation application was accompanied with rapid improvement of objective state, normalization of rhinoscopic pattern and rhinocytogram results in comparison with application of the ointment Levomekol. This tendency has been observed over the whole treatment period.

The objective of the present study was to evaluate the possibility of the application of the cyanoacrylate-based glue for the strengthening of the reconstructed elements of the middle ear and its influence on the regeneration of the cartilaginous tissue. We used the cartilaginous tissue from the auricles of the male California rabbits as a model. The cartilage was destroyed in a standard press. Half of the cartilage thus fragmented was implanted into the left auricle. The remaining part was mixed up with the cyanoacrylate glue and implanted into the right auricle of the same animal. The implanted material was used for the morphological study on day 10, within 1 and 2 months after the beginning of the experiment. The results of the study confirm the absence of the toxic action of the biologically compatible cyanoacrylate-based glue on the regeneration of the cartilaginous and connective tissues which suggests the possibility of its application for the surgical treatment of the diseases of the middle ear.