A system of two coumarin‐based caging groups is presented – one absorbing in the blue (400–450 nm) and the other absorbing in the green (480–550 nm) part of the visible spectrum. Together they form a pair, which allows to selectively photoactivate the one or the other in oligonucleotides. A numerical characterization defining the term “chromatic selectivity” was proposed, and it was shown how chromatically selective uncaging can literally be titrated in a kinetic reaction scheme.