The objective of the work was to evaluate the effect of insecticide and fungicide in the treatment of wheat seeds. The treatments were, T1: control, T2: thiamethoxam (1.5 ml / kg of seed), T3: thiamethoxam (3 ml / kg of seed), T4: pyraclostrobin + methyl thiophanate + fipronil (PTF) (2.0 ml / kg of seed) and T5: PTF (4.0 ml / kg of seed). The treatment with TPF in the dose of 4.0 ml / kg of seed stood out over the other treatments, providing positive effects on the development of the culture, since thiametoxam in the dose of 3.5 ml / kg of seed, showing no difference between treatments, and provided a negative effect on the initial development of the plants.