Dermatomyositis, a connective tissue disorder, is an idiopathic inflammatory myopathy characterised by skin manifestation. The diagnosis of dermatomyositis is based on rashes on the skin, progressive muscle weakness, elevated serum muscle enzymes, abnormal electromyogram, and abnormal findings on muscle biopsy. Hereby presenting this rare case of a 57-year-old female with dermatomyositis with all the typical clinical findings with interstitial lung disease.
Sheehan syndrome is a rare complication of post-partum hemorrhage causing post-partum ischemic necrosis of the pituitary gland. It is a disease with declining incidence, more prevalent in developing countries. The incidence of Sheehan syndrome is 1 in 100,000 births. It was first described by a British pathologist Harold Leeming Sheehan in 1937.We present the case of a 42 year old female who presented with bilateral knee pain for 4 years, on over-the-counter steroids. She gave a history of lactational failure and secondary amenorrhea following childbirth. Her investigations revealed central hypothyroidism and she was diagnosed as Sheehan syndrome.
Eosinophilic esophagitis (EE) is an atopic condition of the esophagus that has become increasingly recognized over the last decade. It is associated with a variety of esophageal symptoms such as dysphagia, food impaction and chest pain. It has a predilection for white males between the age of 30 and 40 years of age. EE is diagnosed based on the combination of typical esophageal symptoms and esophageal mucosal biopsies demonstrating squamous epithelial eosinophil-predominant inflammation. Hereby we present a case of 65-year-old female who presented with dysphagia and gastritis for 12 months duration.
Chronic pancreatitis has a fibro-inflammatory subtype called autoimmune pancreatitis. A combination of imaging tests, including a CT scan and pancreatography, lab tests that check for IgG4 and/or autoantibodies, histological analysis, and a favourable response to corticosteroid treatment are used for diagnosis. Hereby we present a case of a young boy who presented to our hospital with recurrent abdominal pain and on further investigation was found to have elevated levels of IgG4 as well as a developmental abnormality of pancreatic duct known as pancreatic divisum.
Wilson's disease is an inborn error of copper metabolism that is characterized by deficiency of ceruloplasmin, the serum transport protein for copper. Copper is collected in the liver, and after hepatic binding sites are saturated, it is released. Systemic disease then develops and there is abnormal accumulation of copper in the brain, particularly in the putamen and globus pallidus. Presenting this case of a 32-year-old male patient who presented with peculiar features for Wilson’s disease.
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