Osteoporosis is among the common diseases affecting bones, it is usually consider as the commonest one. Poor knowledge about its precipitating factors and the means for prevention will result in increasing the burden of the disease in the community; for this reason, the prevalence of osteoporosis in the world will increase. Methodology: Across-sectional study on 203 women attended Primary Health Care Centers in Al Dora District was conducted for the period from the first of March to end of May 2021, in order to determine their knowledge toward osteoporosis causes, complications and prevention. Statistical analysis .The row data were coded and analyzed by SPSS (version 23) software package then tabulated. Descriptive statistics were used to describe the basic features of the data in this study. Results: The all participants were females aged between 40 and 71 years (Mean ±SD 56.40 ±7.77). The majority of them were married (93.1%). Regarding employment status, 155 of them (76.4%) were housewife and the rest were employed. More than half of the participant’s (108 ,53.2%) had educated level of primary school, were 46 (22.7%) had intermediate school and 44(21.7%) of the with secondary school graduation, the rest were illiterate(5 ,2.5%).