Background: In this analysis, we aimed to systematically compare the procedural and post-operative complications (POC) associated with laparoscopic versus open abdominal surgery for right-sided colonic cancer resection. Methods: We searched MEDLINE, http://www.ClinicalTrials.gov , EMBASE, Web of Science, Cochrane Central, and Google scholar for English studies comparing the POC in patients who underwent laparoscopic versus open surgery (OS) for right colonic cancer. Data were assessed by the Cochrane-based RevMan 5.4 software (The Cochrane Community, London, UK). Mean difference (MD) with 95% confidence intervals (CIs) were used to represent the results for continuous variables, whereas risk ratios (RR) with 95% CIs were used for dichotomous data. Results: Twenty-six studies involving a total number of 3410 participants with right colonic carcinoma were included in this analysis. One thousand five hundred and fifteen participants were assigned to undergo invasive laparoscopic surgery whereas 1895 participants were assigned to the open abdominal surgery. Our results showed that the open resection was associated with a shorter length of surgery (MD: 48.63, 95% CI: 30.15–67.12; P = .00001) whereas laparoscopic intervention was associated with a shorter hospital stay [MD (–3.09), 95% CI [–5.82 to (–0.37)]; P = .03]. In addition, POC such as anastomotic leak (RR: 0.96, 95% CI: 0.60–1.55; P = .88), abdominal abscess (RR: 1.13, 95% CI: 0.52–2.49; P = .75), pulmonary embolism (RR: 0.40, 95% CI: 0.09–1.69; P = .21) and deep vein thrombosis (RR: 0.94, 95% CI: 0.39–2.28; P = .89) were not significantly different. Paralytic ileus (RR: 0.87, 95% CI: 0.67–1.11; P = .26), intra-abdominal infection (RR: 0.82, 95% CI: 0.15–4.48; P = .82), pulmonary complications (RR: 0.83, 95% CI: 0.57–1.20; P = .32), cardiac complications (RR: 0.73, 95% CI: 0.42–1.27; P = .27) and urological complications (RR: 0.83, 95% CI: 0.52–1.33; P = .44) were also similarly manifested. Our analysis also showed 30-day re-admission and re-operation, and mortality to be similar between laparoscopic versus OS for right colonic carcinoma resection. However, surgical wound infection (RR: 0.65, 95% CI: 0.50–0.86; P = .002) was significantly higher with the OS. Conclusions: In conclusion, laparoscopic surgery was almost comparable to OS in terms of post-operative outcomes for right-sided colonic cancer resection and was not associated with higher unwanted outcomes. Therefore, laparoscopic intervention should be considered as safe as the open abdominal surgery for right-sided colonic cancer resecti...
Purpose: One of the most common complications of hyperbaric oxygen (HBO2) therapy is middle ear barotrauma (MEB), occasionally causing otalgia. The objective of this study was to evaluate the effect of dried salted plum consumption on MEB and otalgia associated with HBO2 therapy. Materials and methods: Patients undergoing the first chamber session of HBO2 therapy were included in the present prospective randomized controlled trial. The Valsalva maneuver was administered to all patients before HBO2. The patients were randomly divided into two groups: one that ate a dried salted plum during HBO2 treatment and the other that did not. An otoscopic examination was performed after HBO2 therapy. The MEB was graded according to Teed scores. The degree of otalgia was recorded using the Visual Analog Scale (VAS). Results: Ninety patients were enrolled. The overall incidence of MEB (Teed score grade 1~4) was 39.6% (21 of 53) for patients administered a dried salted plum versus 37.8% (14 of 37) for the control group (P=1.000). The incidence of mild MEB (Teed score grade 1~2) and severe MEB (Teed score Grade 3~4) between the two groups was not significantly different. Otalgia was present in 5.7% (3 of 53) of patients administered a dried salted plum versus 18.9% (7 of 37) for the control group (P=.085). No patients administered a dried salted plum had a VAS score ≥4 for otalgia versus 10.8% (4 of 37) for the control group (P=.026). Conclusions: Dried salted plum consumption does not decrease the incidence of MEB, but may ameliorate the severity of first chamber session HBO2-induced otalgia.
With integrative trend of world economy, drastic competition in the market, commercial intercourse in the future will emphasize more and more on convenience. Thus strengthening the comprehensive transportation network of research and practice has become the mainstream. This paper describes the development of an intelligent traffic control and dispatch system.
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