No abstract

Background: A rare immune-deficient condition is known as nodular lymphoid hyperplasia (NLH). It is not known how common it is, but gene-molecular testing in conjunction with a medical history may definitively identify it. Case summary: A 28-year-old man who had been seeking medical care for sporadic stomach pain throughout the previous years was described in the case. Colonoscopy showed 2 to 4 mm-diameter diffuse nodular hyperplasia of the rectum and ileum mucosa. The Lamina propria had a significant infiltration of lymphocytic inflammatory cells, according to ileal and rectal biopsies.To 0.01g/L, the immunoglobulin A level had drastically dropped.Finally, supplementary testing in conjunction with a whole gene exon test was used to determine the diagnosis of nodular lymphoid histiocytosis. Regular follow-up testing is necessary since this case runs the risk of developing into intestinal lymphoma. Conclusion: This example highlights the fact that abdominal discomfort is a frequent clinical symptom that can be caused by a variety of different conditions, and while NLH is an uncommon disease, doctors are advised not to dismiss it when it is present.