Highly efficient NIR-II photothermal therapy is enabled by molecularly engineered conjugated small molecule nanoparticles.

Singlet–singlet exciton annihilation (SSA) is found to be a critical factor for the decomposition of blue thermally activated delayed fluorescence (TADF) emitters in organic light-emitting diodes (OLEDs).

Stimuli-responsive polymersomes formed by amphiphilic block copolymers have attracted substantial attention as smart and robust containers for drug delivery and nano/micro-reactors. Bio-sourced amphiphilic diblock copolypeptoids were developed that can self-assemble into oxidation-responsive unilamellar vesicles. These vesicles can burst under the action of reactive oxygen species which can be the hydrogen peroxide, or the singlet oxygen produced by light-activation of photosensitizer with spatiotemporal control.Polysarcosine (PSar, also called poly(N-methyl glycine)) was selected as the hydrophilic block, due to its resistance to protein adsorption and low toxicity, similar to PEG. We designed and synthesized poly(N-3-(methylthio)propyl glycine) as the hydrophobic block. Its polyglycine backbone is the same as that of PSar, and especially its hydrophobic N-substituents, thioether side-chains, can be oxidized to hydrophilic sulfoxides. These oxidation-responsive polymersomes entirely based on N-substituted poly(amino acid)s were biocompatible as confirmed by cell viability tests, and may find applications in drug delivery, biosensing, biodetection, and nano-/micro-reactors.The Supporting Information is available free of charge on the ACS Publications website at DOI:… Materials and methods, experimental details, characterization data (PDF).Videos of vesicle disruption under the stimuli of H2O2 or light irradiation (AVI).

A lack of an efficient and stable blue device is a critical factor restricting the development of organic light-emitting diode (OLED) technology that is currently expected to be overcome by employing thermally activated delayed fluorescence (TADF). Here, we investigate the TADF and electroluminescence (EL) performance of six carbazole/triphenyltriazine derivatives in different hosts. A good linearity between lg(LT50/k F 2 ) and the EL emission wavelength is found, where LT50 is the half-life of the devices and k F is the fluorescence rate of the emitters, suggesting the dominance of the singlet exciton energy and lifetime in device stability. An indolylcarbazole/triphenyltriazine derivative (ICz-TRZ) with the capability to suppress solid-state solvation exhibits blue-shifted emission and an increased k F (1.5 × 10 8 s −1 ) in comparison to the control emitters in doped films. ICz-TRZ-based devices achieve a maximum external quantum efficiency (EQE) of 18% and an EQE of 5.5% at a very high luminance of 7 × 10 4 cd/m 2 . Ignoring the poor electrochemical stability of ICz-TRZ, the device offers an LT50 approaching 100 h under an initial luminance of 1000 cd/m 2 and CIE coordinates of (0.14, 0.19). The findings in this work suggest that computer-aided design of high k F TADF emitters can be an approach to realize efficient and stable blue OLEDs.