A practical and efficient monofluoromethylthiolation that employs the typical Bunte salt, sodium S-(fluoromethyl) sulfurothioate, as the sulfur source is described. This reagent reacts readily with a variety of aryl amines and aryl thiols. The high tolerance of functional groups demonstrates the potential of this reaction. In addition, this method is suitable for the late-stage monofluoromethylthiolation of complex bioactive molecules.

A thiol-free protocol is developed for the copper-catalyzed C–X (X = S, Se) cross-coupling of alkynyl carboxylic acids with Bunte salts.

Use of a new odorless, shelf-stable, easy to handle, practical and scalable direct selenylation reagent, NaO2SeR, has been disclosed.

A practical and efficient methylthiolation that employed the typical Bunte salt, sodium S-methyl sulfothioate as sulfur source was described. This reagent could react with a variety of compounds such as...