In the present study, the temperature and moisture content of the output seeds of the cooking pot were considered as inputs or independent variables and the insoluble fine partial content of the extracted oil, moisture content of the extracted oil and obtained meals, as well as the oil content of the achieved meals and acidity value of the extracted oil were considered as responses and were designed. Three different activation functions, including Gaussian membership and triangular as well as trapezoidal were applied and studied. The trapezoidal function with a 3–3 membership function for the three output variables including insoluble fine partials of oil, oil acidity and moisture content of the meals as well as the triangle membership function with 2–2 and 3–3 functions, respectively, for moisture content of the extracted oil and the oil content of the obtained meals were evaluated and detected as optimized models in the current study. The above mentioned models demonstrated higher correlation coefficients (R2) between the experimental and predicted values and the lowest root mean squared errors, confirming the adaptability of the applied models in the present study. Practical applications Today, because of the high demand for crops for extensive application in the human diet, increases in the efficiency of the processing are attracting much more attention. In this regard, discovering and detection of the optimized conditions for processing with the minimum wastes looks very important and economic. Therefore, the uses of predictive methods in different food processes have been considered appropriate tools for improving of the efficiency of the processes as well as the enhancement of the quality of the produced products. In this respect, the ANFIS design as a novel predictive analytic tool, along with Response Surface Methodology (RSM) and Artificial Neural Network (ANN), are applied extensively. Thus regarding the above mentioned content, ANFIS design was applied to predict and optimize some of the selected physico‐chemical properties of the extracted oil through the extraction process. Therefore prediction of the optimized conditions of oil extraction could improve the quality of the extracted oil and performance of the extraction process with the minimum wastes during short and logical extraction time.

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Objectives: Different drugs are prescribed for the induction of ovulation in patients with polycystic ovary syndrome (PCOS). The aim of this study was to compare the effect of letrozole alone with letrozole plus N-acetyl cysteine (NAC) on the pregnancy rate in patients with PCOS. Materials and Methods: This clinical trial studyincluded317 patients with PCOS in the infertility clinic of Zahedan in 2018. Patients were randomly divided into letrozole and NAC plus letrozole groups. Then, several parameters were evaluated in both groups, including the pregnancy rate, number of follicles larger than 18 mm, endometrial thickness, and the endometrial pattern. Finally, data were analyzed using SPSS 25, and t-test and chi-square tests were used for statistical analysis. Results: The mean age of study participants was 28.5 ± 4.9 years old. The mean duration of infertility in the intervention group was 4.5 ± 3.8 years. The mean anti-Müllerian hormone and the mean endometrial thickness of patients in the intervention group were 4.4± 3.6 ng/mL and 7.6 ± 2.5 mm, respectively. Eventually, the pregnancy rate was 14.6% (n = 23) and 7.5% (n = 12) in the intervention and control groups, respectively (P = 0.046). Conclusions:The results of this search revealed that the number of follicles with the size of 18 mm in the control group was higher compared to the intervention group, but the fertility rate in patients with PCOS receiving letrozole plus N-acetylcysteine was significantly higher.

Interruption of the activity of ovary before the age of forty is called premature ovarian failure (POF) in which ovaries lose their follicular and hormonal functions. A decline in the number of ovules before the age of menopause is a physiologic phenomenon. In the present case report, treatment of a patient by POF was reported using traditional Persian medicine principles. In Persian medicine, each humor has its own temperament. A change in the temperament and quality or quantity of these humors causes the disease and therefore modifying the temperament is the milestone of treatment. The patient was a 39-year-old married woman with irregular menstruation cycles and finally, cessation of menstruation. In this period, the patient had vaginal dryness, severe dyspareunia, gastritis, and parasomnia. At first, some instructions were ordered to change her lifestyle, for example, a change in food intakes, enough sleep, and exercise. In addition, several medications were ordered including the digestive system electuary (Majoun Jahaz Hazemeh), Eyaraj Fighara capsule and powder containing Glycyrrhiza glabra roots, Foeniculum vulgare and white sugar, oil massage of the abdomen and flanks, and cupping of the uterus. At the end of treatment, complete rehabilitation was achieved and menstruation irregularity, gastritis, and parasomnia were resolved. Based on the results, if a patient follows the rules and has a healthy lifestyle, inappropriate humor is unable to appear, the healing can be stable, and this disease or similar melancholic disorders fail to occur

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