AbstrakLuka adalah hilang atau rusaknya sebagian jaringan tubuh yang menyebabkan gangguan kontinuitas jaringan tersebut. Lidah buaya telah digunakan sebagai pengobatan tradisional diberbagai kebudayaan diseluruh dunia. Tujuan penelitian ini adalah untuk melihat pengaruh gel lidah buaya terhadap penyembuhan luka, yang ditinjau dari jarak pinggir luka. Penelitian ini merupakan penelitian eksperimental dengan post-test only control group design. Subjek penelitian terdiri dari 24 ekor tikus Wistar betina yang dibagi menjadi empat kelompok; satu kelompok kontrol dan tiga kelompok perlakuan. Kelompok kontrol diberikan NaCl fisiologis sebagai terapi luka sedangkan kelompok perlakuan diberikan gel lidah buaya dengan berbagai frekuensi pemberian. Hasil penelitian menunjukkan bahwa pemberian olesan gel lidah buaya tidak memberikan pengaruh yang signifikan terhadap penyembuhan luka. Pada setiap variabel jarak pinggir luka terlihat bahwa kelompok kontrol memiliki hasil penyembuhan luka yang lebih baik dari hari ke hari.Secara umum, pada tujuh hari pertama (fase hemostasis dan inflamasi) ukuran jarak pinggir luka memiliki perbedaan yang bermakna (p<0,05). Pada hari-hari selanjutnya pada fase proliferasi, ukuran jarak pinggir luka secara umum tidak memiliki perbedaan yang bermakna (p>0,05). Kesimpulan penelitian ini adalah pemberian gel lidah buaya tidak lebih efektif dibandingkan NaCl fisiologis terhadap penyembuhan luka yang ditinjau dari jarak pinggir luka. Kata kunci: gel lidah buaya, penyembuhan luka, jarak pinggir lukaAbstract A wound is a laceration or break in the living tissue which causes continuity damage within the tissue. Aloe vera has been used for traditional medication in many cultures all over the world. The objective of this study was to see the effect of Aloe vera gel on wound healing based on the wound edge distance. This research was experimental with post-test only control group design. Twenty-four female Wistar rats were divided into four groups; one control group and three treatment groups. The control group was given fisiological NaCl solution for open wound therapy and treatments groups were given Aloe vera gel with varying frequencies of application. The results shows that Aloe vera wasn't have a significant effect on wound healing. In each variable of wound edge distance, results show that the control group heals better from day to day. As seen in the general, in the seven first days (hemostatis and nflammation phase), the distance of wound edge was significantly different (p<0.05). In the following days (proliferation phase), the distance of wound edge generally wasn't significantly different (p>0.05). The conclusion of this study is Aloe vera gel isn't effective when compared to fisiologic NaCl solution in healing the wound, based on the wound edge distance.

Acute hepatitis C (HCV) infection has been identified as an important cause of fulminant hepatic failure (FHF), characterized by rapid deterioration of liver function from massive hepatic necrosis leading to encephalopathy and multi-organ failure. We admitted a female patient at Shalamar Hospital with jaundice, fever, encephalopathy and coagulopathy of short duration with no history of any comorbidity. Her hepatitis viral screen revealed positive anti HCV. Her viral loads were also high. A diagnosis of FHF due to acute HCV infection was made. Patient was treated conservatively and improved gradually. In summary, acute HCV can cause FHF and should be ruled out in patients with FHF of unknown cause in an endemic country for HCV like Pakistan.

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Background: Being a developing country, fertility rates are high in our country while contraception use is sub-optimal. Aim: To assess the factors and perceptions of women of reproductive age influencing their choice of contraceptive method as well as the prevalence of contraception. Duration & place of study: Mohi-ud-Din Islamic Medical College, Mirpur, AJK from January to June 2021 Methods: In this cross-sectional study, females of child-bearing age were selected. They were divided into various groups based on different parameters. Pre-structured and a pre-validated proforma was used to collect data. Results: Most of the females, 74.88%, were between the ages of 21-40 years. Most of the women were literate and 50.51% had completed their matriculation. Majority of them, about 49.69%, have 2-4 children. The working status revealed that 74.95% women were house wives while only 25% were doing a job and 85.06% were Muslims. The proportion of women belonging to low-income group was only 8.76% while the average was almost similar for women belonging to middle- and high-income group. Media exposure was quite high in the study subjects with about 92.60% reported to have had media exposure. Conclusion: There is restricted and reduced use of contraceptive methods among our study subjects. Among those who use contraception, preferred methods are short acting ones. Keywords: Contraception, women, method choice, family, planning