Several neurological disorders, including Parkinson's disease, schizophrenia, human immunodeficiency virus infection, and restless leg syndrome, majorly result from disruption in the dopamine (DA) level.

Herein, we have developed highly sensitive and selective non-enzymatic bioinspired polydopamine derived nitrogen rich carbon (NC) coated bimetallic zeolitic imidazolate framework (BM-ZIF) electrochemical sensor via simple hydrothermal approach for monitoring adrenaline (AD) from COVID-19 quarantined person blood and pharmaceutical sample. The designed NC-BM-ZIF elec-trode shows excellent sensitive and selective performance towards AD monitoring with detection limit (LOD) of 0.01 nM and 0.1931 μA/nM/cm 2 sensitivity over a wide linear range of 50-1625 nM. To the best of our knowledge, this is the first study of using of NC-BM-ZIF electrode for the electrochemical sensing of AD from quarantined person blood and pharmaceutical sample.