This paper provides an insight about the significance of the enterprise technical architecture (ETA) in enabling and supporting the implementation of the South African National Health Insurance (NHI). Design: Existing documentations from both academic and government domains were gathered, and analyzed using the hermeneutics technique, from the perspective of interpretivist approach. Based on the analysis, the paper reveals the cruciality of the ETA in the implementation of the Universal health coverage (NHC) in the South African environment. The paper is intended to be of use for the core stakeholders of the NHI, which include governments' administrations, IT specialists, health practitioners, as well as academics.