Background: Individuals with intellectual disability (ID) are mostly neglected and hardly exercised. The purpose of this study was to investigate the effect of a combined program (aerobic and rebound therapy) with two different ratios on some physical and motor fitness indices in intellectually disabled girls.Material and methods: A total of 24 girls with ID (13-17 years old with an IQ of 50 to 70) were selected and randomly divided into two experimental and one control group. Experimental groups performed a combined aerobicrebound therapy program with two different proportions: (group 1 performed 10 minutes of aerobic exercises and 20 minutes of rebound therapy, group 2 performed 20 minutes of aerobic exercises and 10 minutes of rebound therapy) for 8 weeks (3 sessions per week). All physical and motor fitness tests including endurance performance, lower extremities endurance, cardio-respiratory endurance, static and dynamic balance, agility and coordination were taken before and after the training period. Data were analyzed using Shapiro-Wilk's tests, covariance and variance analysis with repeated measurements (α = 0.05). Results:The results showed that both exercise programs in experimental groups improved endurance performance indices, lower extremities endurance, cardio-respiratory endurance, static and dynamic balance, agility and coordination in comparison to the control group. No significant differences were observed between the two experimental groups. Conclusions:In conclusion, to improve motor and physical fitness indices in girls with ID, both combination programs (aerobic-rebound therapy) with different proportions can be used.