Background:The IMP3 is an oncofetal protein, which has been recently proposed as a diagnostic and prognostic marker in many cancers, including colorectal adenocarcinoma. The overexpression of IMP3 seems to have a correlation with patient's prognosis. Objectives: In this study, the relationship between IMP3 expression in colorectal adenocarcinoma and clinicopathologic findings was assessed. Patients and Methods:In this study 112 colorectal tumor paraffin blocks of Rasoul-e-Akram hospital were stained for IMP3 and slides were assessed for intensity and extent of positivity. The statistical relationships between marker expression and clinicopathologic findings (degree of differentiation, tumor size, depth of invasion and lymph nodes metastasis) were assessed. Data were analyzed by the SPSS 21 software and logistic regression and chi-square test, with p-values of less than 0.05 indicating statistical significance. Results: Immunoreactivity pattern of IMP3 was cytoplasmic in different clinicopathologic findings. Among different clinicopathologic findings, we found a statistical relationship between tumor differentiation and IMP3 (P = 0.047); so that, the poorly differentiated tumors were positive for this marker. No relationship was found between tumor size, depth of invasion or lymph node involvement and IMP3. Conclusions: IMP3 immunoreactivity was associated with poor differentiation of tumor yet not associated with tumor size depth of invasion or lymph node involvement.

The relationships between somatic growth and otolith dimensions, otolith size to estimated age and growth parameters of the tigertooth croaker (Otolithes ruber) were investigated in 100 specimens (size range: 19.1-52.0 cm, total length) from the Oman Sea area, September 2014. All 100 otoliths were sectioned and determined by age.The oldest specimen was a 4.5-year-old female with a total length of 40.6 cm; the youngest specimen was also a female estimated at 1 year of age with a total length of 19.1 cm. The von Bertalanffy growth equation was estimated as L t = 54.70 (1 − exp (−0.37 (t + 0.21))). Concluded was that there is a significant relationship between body size, otolith dimensions and estimated age of Otolithes ruber.