BACKGROUNDCOPD is characterised by frequent exacerbations, mostly infective. These are usually treated with antibiotics, even when the aetiology is non-infective. The efficacy of antibiotics in this setting is controversial. Hence, the study was planned to look for any added advantage for antibiotics in COPD exacerbations. Aim-To study the usefulness of antibiotics in acute exacerbations of COPD in a) reducing relapse of exacerbation and b) reducing duration of hospital stay.