Cutaneous squamous cell carcinoma is a relatively uncommon type of skin cancer that occurs most frequently on the hands. An 84-year-oldright-handedwomenpresented a recurrent cSCC of the 3rd finger four months following amputation and after declining adjuvant radiotherapy indicated given insufficient limits. Salvage hypofractionated Radiotherapy was performed with the 3D technique (60 Gy of RT in 20 fractions, at a daily dose fraction of 3 Gy over four weeks), with complete response and good aesthetic results.

Vaginal melanomas are extremely rare gynaecological malignancy and very aggressive tumor. There is no standardized treatment owing to the extreme rarity of the disease. The prognosis of vaginal primary melanoma is very poor despite treatment modality, because most of the cases are diagnosed at advanced stage. This paper details the clinical course of 2 patients with primary vaginal melanoma treated by definitive radiation therapy, this report includes also a summary of available treatments of this uncommon disease, with focus on the role of radiotherapy.

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The extraskeletal myxoid chondrosarcoma (CME) is a rare malignant soft tissue tumour described as a distinct clinical, histological, immunohistochemical, genetical and evolutive entity. It represents only 2.5% of soft tissue sarcomas. Its individualization is important because it has a long and indolent clinical course, and tumour-related death often occurs after a long survival period. The diagnostic key is morphological supported by immunohistochemistry and genetics t (9; 22) that allow differentiating it from other tumours with myxoid stroma and from chordoma. This report describes a patient with paravertebral extraskeletal myxoid chondrosrcoma with a high locoregional extension.