ÖzetEritema nodosum genellikle tibia ön yüzünde yerleşen kırmızı-mor renkte nodüllerle görülen subkutan dokunun inflamatuvar bir lezyonudur. Çocuklarda sıklıkla streptokokkal enfeksiyonlar ve primer tüberküloz ile birlikte görülür. Eritema nodosum tanısı esasen klinik olarak konan bir hipersensitivite reaksiyonudur. Suçiçeği çocukluk çağının sık görülen bir enfeksiyon hastalığıdır. Biz geçirilmiş varisella enfeksiyonu sonrası eritema nodosum gelişen okul çocuğu olguyu sunmak istiyoruz. 6 yaş 7 aylık kız hasta on gündür devam eden her iki bacakta kırmızı renkte şişlikler yakınması ile başvurdu. Onbeş gün önce doktor tanılı suçiçeği geçirme öyküsü vardı. Fizik muayenesinde her iki bacak ön yüzünde kırmızı-morumsu, deriden kabarık, ağrılı, yaklaşık 1-2 cm çaplı nodülleri mevcuttu. Varisella zoster IgM ve IgG'si pozitif bulundu. Hastada mevcut öykü ve varisella serolojisi ile varisella enfeksiyonu sonrası EN geliştiği düşünüldü. AbstractErythema nodosum which is seen red-purple noduls on the anterior surfaces of tibia is an inflammatory lesion of subcutaneous tissue. It is encountered with streptoccoccal infections and primary tuberculosis in children. Erythema nodosum clinically diagnosed is a hypersensitivity reaction. Varicella is an infectious disease which is commonly seen in childhood. We want to present a school-aged child case who developed erythema nodosum following varicella infection. A 6.5 year -old girl was admitted with the complaints of red color swellings on both legs for 10 days. Fifteen days ago she was diagnosed as varicella by the physician. On the physical examination, red-purple, raised from skin, painfull, 1-2 cm in diameter noduls were found on the anterior surface of legs. Varicella zoster IgM and IgG were detected positive. According to the her past history and varicella serology erythema nodosum secondary to varicella infection was considered. (J Pediatr Inf 2016; 10: 159-61)
Objective: Patients with inherited bleeding disorders faced problems in accessing healthcare during coronavirus disease 2019 pandemic. This study aimed to investigate the health problems of patients with inherited bleeding disorders during the coronavirus disease 2019 pandemic. Material and Methods: Children and adult patients with inherited bleeding disorders who had a coronavirus disease 2019 infection between March 2020 and November 2021 were retrospectively evaluated. Results: Seven hundred seventy-two patients were reviewed, and 65 patients who had a coronavirus disease 2019 infection (Male/Female: 58/7, mean age 28.2 ±14.1 years) were analyzed. Sixty patients (92%) had hemophilia A or B or von Willebrand’s disease and 5 (8%) had rare bleeding disorders. Sixteen (24.6%) patients had a comorbid disease and 6 (9.2%) needed hospitalization due to severe coronavirus disease 2019 infection. Seven patients (10.7%) experienced a bleeding episode and were treated with factor concentrates. Totally, 64 (98.46%) patients recovered from the coronavirus disease 2019 infection and 1 died. Conclusion: Patients with inherited bleeding disorders and coronavirus disease 2019 infection mostly had a mild/moderate course of the disease.
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