This clinical trial was recorded on the National Library of Medicine registry (NCT01517828).

FANS, which is reliable and valid, is the first scale to score pain in preterm newborns when facial expression is not accessible.

Ductal persistence and flow pattern did not affect PI but did affect PVI in preterm neonates of less than 29 weeks of GA. Future studies are needed to establish the usefulness of PVI in the early detection and management of PDA in preterm neonates.

The helmet was a satisfactory interface for CPAP delivery in young infants in more than two-thirds of the cases. Pressure sores can be prevented by placing a cushion in the helmet. Caregivers need to take into account the high humidity and noise levels of this interface.

No abstract