Candida albicans is involved in periodontal disease, which is influenced by sex hormones. Aim: To study the effects of the estrogen antagonist tamoxifen (TAM) on periodontal disease of oncological patients; clinical oral strains of C. albicans. Patients: With periodontitis and breast cancer and other with AIDS were used. Materials & methods: Periodontal disease was evaluated by the academy of periodontology procedures and the growth of clinical C. albicans isolates were evaluated by the Clinical and Laboratory Standards Institute techniques. Results: Women who consumed TAM for more than 2 years decreased periodontitis severity. In vitro, TAM inhibited the growth of both fluconazole-sensitive and resistant C. albicans. Conclusion: Administered TAM chronically improves periodontal health and has antifungal activity on oral strains isolated from patients with odontologic and medical pathologies.
El objetivo de este estudio de tipo observacional en la cual se examinaron 160 radiografías panorámicas, fue encontrar, describir, evaluar la prevalencia y comparar la frecuencia de patologías que no sean de origen dental y que puedan ser de importancia para el odontólogo y personal médico como también para el paciente, en este se hallaron patologías como placas de ateroma, apófisis estiloides alargada, osteoescleros idiopática, tonsiolitos, sialolitos, calcificaciones de nodos linfáticos, patologías que no son observadas generalmente por el odontólogo y que en algunos casos puedan ser de vital importancia para la salud del paciente.
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