Primeira submissão em 16/04/11 Última submissão em 29/10/11 Aceito para publicação em 05/12/11 Publicado em 20/02/12 Russell body gastritis (RBG), which can be associated with Helicobacter pylori (HP) infection, is a recently acknowledged lesion characterized by the presence of eosinophilic intracytoplasmic inclusions in plasmacytes. Herein the authors discuss the morphological aspects of a case of RBG in a male patient with clinical complaint of epigastric pain. Upper endoscopy revealed areas of erythema/edema in the antrum. As far as microscopy is concerned, a mononuclear inflammatory infiltrate was identified on the lamina propria, with plasma cells containing Schiff acid periodic (PAS) positive eosinophilic intracytoplasmic globules, which showed positive immunostaining for CD79a, CD138, and kappa/lambda light chains. HP was identified by Giemsa stains.
The aim of this paper is to describe the clinical, histopathological and immunohistochemical findings of a mammary carcinoma in a 22year-old, 10 month pregnant, thoroughbred mare. The clinical examination of the right mammary gland showed a firm enlargement and purulent discharge from the ulcerated skin surface and the teat. During necropsy visceral metastases were not found but inguinal lymph nodes presented metastatic infiltrations when observed histologically. None of the previous reports found positive immunohisthochemical reactions for estrogen and progesteron receptors in an equine mammary adenocarcinoma. However, the findings of positive immunoreactivity to steroid receptors could suggest a hormonal influence on the genesis of the mammary neoplasm, as demonstrated in human breast cancer.
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