Currently, with the perspective of becoming the second leading cause of disease in the world, depression is seen as a disease of modern society, affecting even health professionals such as nurses, nursing technicians, and nursing assistants. Based on this, this work aims to survey data on the use of antidepressants in the clinical nursing staff – nurses, technicians, and assistants who work at night at the ABHU. A questionnaire was designed to understand the reason for using antidepressants in the clinical nursing staff – nurses, technicians, and assistants. In addition, the questionnaire also aims to confirm hypotheses such as, whether the use of antidepressants by health professionals is related to the length of experience in the area, the use of antidepressants is related to stress, physical and emotional exhaustion, the length of treatment with antidepressants with a perception of improvement, it is related to the time of use, whether there is a relationship between the use of antidepressants and gender and whether the treatment with antidepressants is carried out with monitoring of professionals.