METHODS:Fifty four rats were used, distributed into three groups randomly: aroeira, babassu and control, which were divided into three subgroups (six animals) according to the time of the deaths (7, 14, 21 days). All underwent the same surgical procedure, cecotomy and cecorrhaphy. The animals in group aroeira and babassu received daily dose of 100 mg/kg of hydroalcoholic extract and 50 mg/kg of aquous extract respectively, by gavage. The control group received only saline solution. The parameters evaluated were: macroscopic changes, ,resistance test to air insufflations and histological changes. RESULTS:All animals showed good healing without infection. All groups presented adhesions between cecum and neighboring organs.The resistance test insufflating of atmospheric air showed progressive increase of pressure according to the days in the aroeira group, and decrease in babassu group, without significant difference. Microscopy showed significant difference in the polymorphonuclear, hyperemia, angiogenesis, fibroblast proliferation and collagen histological variables in the 14 th day. CONCLUSION:Hydroalcoholic extract of aroeira and the aqueous extract of babassu favored the healing process in cecorrhaphy in rats.
PURPOSES: To evaluate whether polyurethane foam leads more intense foreign-body reaction than silicone foam. To compare the vascularization of the capsules surrounding the foam implants. To investigate if the capsule of polyurethane foam implanted has greater amount of collagen than that of silicone foam. METHODS: Sixty-four young male Wistar rats were allocated into two groups: polyurethane foam and silicone foam. Subcutaneous discs were implanted into the dorsum of the animals in both groups. The capsules were assessed 28 days, two months, three months and six months postoperatively. Microscopic analysis with H&E stain was performed to evaluate the acute and chronic inflammatory process, foreign-body reaction and neovascularization. The analysis with picrosirius red was performed using the ImageProPlus software, to measure the number of vessels and collagen types I and III. RESULTS: There were no statistical differences between the two groups regarding the acute and chronic inflammatory processes. All rats from the polyurethane group, in all times, exhibited moderate or intense foreign-body reaction, with statistic significant difference (p=0.046) when compared with the silicone group, in which the reaction was either mild or nonexistent at two months. Vascular proliferation was significantly different between the groups at 28 days (p=0.0002), with the polyurethane group displaying greater neovascularization with H&E stain. Similar results were obtained with picrosirius red, which revealed in the polyurethane group a much greater number of vessels than in the silicone group (p=0.001). The collagen area was larger in the polyurethane group, significantly at 28 days (p=0.001) and at two months (p=0.030). CONCLUSIONS: Polyurethane foam elicited more intense foreign-body reaction when compared with silicone foam. The number of vessels was higher in the capsules of the polyurethane foam implants 28 days after the operation. The capsule of the polyurethane foam implants showed a greater amount of collagen than that of the silicone foam implants.
Background: Obesity is a chronic disease and has become the most prevalent public health problem worldwide. The impact of obesity on knee is strong and the BMI is correlated with the different alterations. Aim: Compare surgical visualization of arthroscopic field in partial meniscectomy in obese and non-obese. Method: Sixty patients were selected, 30 obese and 30 non-obese who underwent arthroscopic partial meniscectomy. The arthroscopic surgical procedures were recorded and analyzed. For the analysis of visualization was used the Johnson's classification (2000). Results: Were analyzed 48 men and 12 women, the average age was 42.9 years with BMI between 21.56 to 40.14 kg/m2. The distribution of visibility of the surgical field according to the classification was: grade 1 - 38/60 (63.3%); grade 2 - 13/60 (21.6%); grade 3 - 6/60 (10%); grade 4 - 3/60 (5%). Conclusion: Knee arthroscopy did not show a significant difference in the visibility of arthroscopic field in obese and non-obese patients. Thus, it should not be indicated as the preferred method of diagnostic evaluation of joint changes in these patients.
InTRODUÇÃOO câncer de esôfago está entre as seis neoplasias malignas mais comuns no mundo, e é considerado pela Organização Mundial de Saúde importante problema de saúde pública. Devido a sua grande agressividade clínica, constitui um dos tumores de pior prognóstico, com alto índice de morbi-mortalidade 6 .Sua incidência varia em diferentes regiões do mundo, alcança seus maiores índices em países asiáticos como a China, sendo também freqüente no Japão, sudeste da África e América do Sul 9 . No Brasil, de acordo com a estimativa de incidência de câncer para 2006 7 , devem ocorrer cerca de 10.580 novos casos (7.970 entre os homens e 2.610 entre as mulheres) neste ano. O Estado do Rio Grande do Sul apresenta um dos maiores índices mundiais, com 21,17 casos para cada 100 000 homens e 7,88 para cada 100 000 mulheres 7 .Dentre os diferentes tipos de tumores que podem acometer o esôfago, o mais freqüente, e que responde por mais da metade dos tumores deste órgão na estatística mundial, é o carcinoma epidermóide, também chamado espinocelular, pois origina-se do epitélio normal de revestimento do esôfago . ABCDDV/570O estudo da biologia molecular dos tumores tem despertado o interesse de grande número de pesquisadores, uma vez que possibilita maior compreensão da gênese tumoral, abrindo grande número de linhas de pesquisas na busca de melhor manejo tanto na prevenção, quanto no diagnóstico, prognóstico e, conseqüentemente na conduta em relação ao câncer 9 .Ainda em investigaçã, técnicas de biologia molecular parecem ter futuro promissor no diagnóstico patológico e graduação de tumores. Estudos de marcadores de angiogênese são exemplos de um importante coadjuvante na pesquisa do câncer, e têm demonstrado forte correlação com a intensidade da carcinogênese 5,8 .Os biomarcadores que modulam a formação de novos vasos pela angiogênese, como o C34, uma glicoproteína transmembrana expressa em todas as células progenitoras hematopoéticas, têm sido avaliados em diversos tipos de tumores como marcador de grande potencial prognóstico1, uma vez que a angiogênese é reconhecida como pré-requisito fundamental para o crescimento e metastatização tumoral 4 .Associado à imunoistoquímica, a citofotometria de
CT CT CT CT findings in patients submitted to findings in patients submitted to findings in patients submitted to findings in patients submitted to findings in patients submitted to Roux-en-y gastric bypass without ring Roux-en-y gastric bypass without ring Roux-en-y gastric bypass without ring Roux-en-y gastric bypass without ring Roux-en-y gastric bypass without ring Achados tomográficos das alterações abdominais pós-operatórias dos pacientes Achados tomográficos das alterações abdominais pós-operatórias dos pacientes Achados tomográficos das alterações abdominais pós-operatórias dos pacientes Achados tomográficos das alterações abdominais pós-operatórias dos pacientes Achados tomográficos das alterações abdominais pós-operatórias dos pacientes submetidos ao derivação gastrojejunal em Y-de-Roux sem anel submetidos ao derivação gastrojejunal em Y-de-Roux sem anel submetidos ao derivação gastrojejunal em Y-de-Roux sem anel submetidos ao derivação gastrojejunal em Y-de-Roux sem anel submetidos ao derivação gastrojejunal em Y-de-Roux sem anel FERNANDA We studied 40 CT exams from patients attended at the radiology service with the intention to clarify abdominal complains. The patients were in post-bariatric surgical follow-up and were operated in the same hospital. We excluded patients who had undergone bariatric surgery by other surgical techniques, operated by another surgical team and the ones who did not agree with the administration of oral or intravenous iodinated contrast media and exceeding the weight limit of the examination table. Results Results ResultsResults Results: The patients were aged from 23 to 70 years, 11 male and 29 female. There were no extra-abdominal changes, and 30 of the 40 patients had CT findings within normal limits. The presence of stenosis at the gastrojejunal anastomosis was found in one patient, internal hernias occurred in five, anastomotic leak in one and the presence of abscess occurred in three of patients. ConclusionConclusion Conclusion Conclusion Conclusion: Total abdominal CT failed to inform the cause of the symptoms in 87.5% of patients seeking medical re-evaluation for symptoms of post-operative bariatric surgery. Due to the need for more effective intervention in the clinical management of severe obesity, the indications for bariatric operations have been growing 5 . The surgical treatment for severe obesity has been employed for nearly half a century. It began in the 1950s with operations that caused malabsorption, abandoned in the late 1970s due to their serious side effects. From then on, procedures that limit food intake began to dominate, either by simply restricting the capacity of the stomach, or by its division and anastomosis to the proximal jejunum 6 . Among the surgical techniques currently considered for treatment of morbid obesity, Roux-en-Y gastric bypass is widely used 2,6,7 . With the increase in the frequency of bariatric operations, it is necessary that the radiologist must be aware The postoperative radiological study, the survey of complications an...
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