Introduction: Primary open-angle glaucoma (POAG) shows an exponential growth related to age. Prostaglandin analogues are first-line drugs. As a side effect, they cause elongation, pigmentation and thickening of the eyelashes. Demodex are ectoparasites that live in the skin of humans and are associated to blepharitis. Their rate of infestation increases with age. Aim: Analyze and compare the prevalence of eyelid infestation by Demodex in patients with POAG who attend the clinic in a random manner, and who are receiving treatment with prostaglandin analogues. Methods: 110 eyes treated with prostaglandin analogues for POAG were included. An eyelash was removed to analyze it under the microscope and observe the presence of infestation. The results were compared with a group of patients with similar characteristics who did not use this drug. In addition, an in vitro study with one drop of different prostaglandin analogues on a slide of samples infested with Demodex was carried out to evaluate the direct chemical effect. Results: 36.4% of patients with POAG treated with prostaglandin analogues were infested with Demodex. The in vitro study showed the morphological changes that the mites suffered. Conclusions: Although the average age was high in the group of patients studied, a low prevalence of Demodex eyelid infestation was observed, unlike other series of patients of the same age who did not receive this medication and had a higher prevalence of infestation.

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The two procedures were comparably safe and effective in treating mild to moderate myopia under this protocol. Eyes that had PRK were somewhat more myopic at 1 year after surgery, attributable to the older PRK ablation algorithm. Adoption of newer (current) laser algorithms has improved the predictability of PRK. There was also evidence of reduced variability of outcome in the PRK group. The PRK eyes did not exhibit hyperopic shifts during the 1 year follow-up.

BACKGROUND: During the last decade, new refractive surgery procedures have been introduced; older techniques have been modified or even abandoned. Cryolathe myopic keratomileusis has been in clinical use for approximately 30 years. In this retrospective study, we present our experience in applying this technique for the correction of 4.00 to 6.00 diopters of myopia. METHODS: Autoplastic cryolathe keratomileusis was performed on 61 eyes of 44 patients who were at least 18 years of age, with a preoperative myopia of 8.00 D or less, and 4.00 D or less of astigmatism. The surgical technique used the Barraquer microkeratome and cryolathe. The mean postoperative observation period was 28 months (range, 12 to 73 months). RESULTS: The mean preoperative spherical equivalent refraction was -5.95 ± 1.14 D (range, -4.25 to -8.00 D). After a mean follow up of 28 months, the mean postoperative spherical equivalent refraction was -0.91 ± 1.49 D (range, +2.00 to -7.75 D). At the end of follow up, 37 eyes (60.7%) were within ±1.00 D of emmetropia and 44 eyes (72.1%) achieved 20/40 or better uncorrected visual acuity. Complications included corneal ectasia in one eye (1.6%) and epithelial inclusions of the interface in another eye (1.6%). Irregular astigmatism was not a major problem, occurring in only two eyes (3.3%). CONCLUSIONS: Cryolathe keratomileusis is a proven and feasible technique for correcting moderate to high amounts of myopia in properly selected patients; there is a low incidence of vision -threatening complications. Refract Corneal Surg 1993;9:259-267.) RÉSUMÉ INTRODUCTION: Pendant la dernière décade de nouvelles chirurgies réfractives ont été introduites; les méthodes précédentes ont été modifiées ou abandonnées. Le keratomileusis myopique reste parmi les techniques opératoires qui ont duré pendant des années. Dans cette étude rétrospective nous présentons notre expérience avec cette technique pour correction de la myopie entre quatre et huit dioptries. MÉTHODES: Le keratomileusis autoplastique au cryo-tour fut réalisé sur 61 yeux de 44 patients âgés d'au moins 18 ans et affectés d'une myopie préopératoire jusqu'à 8,00 dioptries avec astigmatisme égale ou inférieur à 4,00 dioptries. Il s'agit du microkératome de Barraquer et le cryo-tour. Le suivi post- opératoire moyen fut de 28 mois (écarts 12 à 73 mois). RÉSULTATS: Le moyen équivalent sphérique de la réfraction préopératoire fut -5,95 ± 1,14 D (écarts -4,25 à -8,00). Après le suivi postopératoire moyen de 28 mois l'équivalent sphérique fut -0,91 ± -1,49 D (écarts +2,00 à -7,75 D). Finalement, 37 yeux (60,7%) étaient entre ± 1,00 D de l'emmetropie et 44 yeux (72.1%) ont réalisés une meilleure acuité visuelle noncorrigée d'au moins 20/40. Les complications comprenaient l'ectasie cornéene chez un oeil (1 ,6%) et les inclusions epitheliales dans l'interface chez un autre (1,6%). L'astigmatisme irregulier n'était pas un grand problème, arrivant chez seulement deux yeux (3,3%).

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