Average motion and patient set-up uncertainties during radiotherapy treatment were found to be limited. However, uncertainties were larger for the cranio-caudal direction and outliers were found in all orthogonal directions. When having available 4D-CT and CBCT information, the use of patient-specific and anisotropic safety margin expansions is advised for both target volume and OAR.
HighlightsEstablishing MRI-only RTP workflows requires synthetic CTs for dose calculation.This study evaluates the feasibility of using a multi-atlas CT synthesis approach.The proposed method was validated on head and neck and prostate cancer patients.Results showed an accurate bone estimation for future patient positioning.Results showed that synthetic CTs are suitable to perform clinical dose calculations.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.