Understanding crop water use under changing climate condition is very important for developing irrigation projects to expand agricultural productivity. This study focus on climate change impact on irrigated crop water use of major grown crops and water demand for irrigation in Anger sub-basin, Ethiopia. Single GCM from Coupled Model Inter-comparison Project Phase 5 with single regional climate model and delta change bias correction approaches were used to project crop water requirement for the developed scenario over the study periods of 2020s and 2080s and demand analysis for the current conditions. The result of the analysis shows that at the 2020s crop water requirement of the irrigated crops changes from the baseline period by 1.7% to 3.83% and 1.5% to 3.8% for RCP 4.5 and RCP 8.5 respectively. At 2080s it changes from 3.36% to 7% and 3.58% to 12.7% for RCP 4.5 and RCP 8.5 respectively over the study area for all crops in the future respectively. Additionally, the demand analysis shows that at the current condition irrigation water demand was 2.096Bm 3 which takes a lion's share with about 62% followed by environmental water demand about 35% and domestic and livestock shares the lowest water demand of 1.72% and 1.475% respectively over the sub-basin. This indicates crop water requirement is increasing due to climate change which is directly influencing the water demand of other sectors. Therefore, in the future period decrement of water resource due to climate change requires water management practices to keep water demand in place to continue agricultural practices and future development plans of agriculture in the sub-basin.