This study aims to analyze the effect of unemployment and economic growth (PDRB) on poverty in Java in 2012-2017 using the zakat variable as a moderating variable. This study uses secondary data types with the panel data model, namely annual data from the variable unemployment, economic growth (PDRB), zakat and poverty from six provinces in Java. Furthermore, the data were tested using multiple linear regression models and moderated regression analysis (MRA) with the help of SPSS version 16. The results showed that unemployment had a significant positive effect, economic growth (PDRB) had no significant positive effect, while the only zakat was able to moderate the unemployment variable towards poverty, and was unable to moderate economic growth variable (PDRB) to poverty.