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Background and aimsPeriodontitis is a common chronic adult condition that implicates oxidative damage to gingival tissue, periodontal ligament and alveolar bone. This study aimed at assessing the association between the nitro-oxidative stress and the periodontal tissues destructions in experimental rat periodontitis.MethodsPeriodontitis was induced in 15 male albino rats by repetitive lesions to the gingiva adjacent to the inferior incisors, performed daily, for 16 days. On D1, D3, D6, D8, and D16 the onset and evolution of periodontitis were monitored by clinical and histopathological examinations; blood was collected and serum nitro-oxidative stress was evaluated through total nitrites and nitrates, total oxidative status, total antioxidant capacity, and oxidative stress index.ResultsThe results demonstrated that there was a graded and continuous increase in serum levels of total nitrites and nitrates, total oxidative status and oxidative stress index, which was consistent with the severity of periodontal destructions during periodontitis progression. However, total antioxidant capacity was not significantly influenced by the disease progression.ConclusionsIn experimental rat periodontitis, the systemic nitro-oxidative stress was associated with the severity of periodontal destructions assessed clinically and histopathologically. Therefore, systemic nitro-oxidative stress parameters might be used as diagnostic tools in periodontitis.

The results suggest that the anesthetics do not present a considerable hepatotoxicity. The comparative assessment of the two anesthetics shows that sevoflurane is superior to isoflurane.

The aim of this study is to assess Hassall's corpuscles in lamb. Thymus samples were harvested from 10 lambs (3 months old) and histologically processed. From the harvested samples, 5 μm seriated sections were made, stained with Goldner's trichrome method and examined under light microscope. In the medulla of the thymic lobules there are on average 7-8 highly polymorphic Hassall's corpuscles. The majority of the corpuscles (80%) have a diameter between 5 and 50 μm, 15% between 50 and 100 μm and only 5% have a diameter of over 100 μm. Only 20-25% among them have a typical "onion-like" structure, 40-45% present different keratinization degrees and 3-5% are cavitary corpuscles, containing degenerated cell fragments. Hassall's corpuscles in lamb are numerous and highly polymorphic.

Aneurysmal bone cyst in an elderly patient is a rare condition.