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As life expectancy increases, so does the number of Ambient Assisted Living (AAL) initiatives. The Living Usability Lab is a user-centered living laboratory aimed at open-innovation and evaluation of new approaches to AAL applications and services, where the different stakeholders may develop and evaluate innovative services for the elderly in near-real life conditions. These AAL initiatives often traverse several research fields, from embedded devices to multiple data streams analysis. Advanced processing, reasoning, and storage of such data streams poses a complex problem usually solved using local processing and storage resources. This chapter presents an overview of the LUL initiative, its services, and applications, and explores the problem of advanced processing, reasoning, and storage from a cloud computing perspective.