A double-blind paired comparison was made of once daily and three times daily regimens of 0.1% halcinonide cream in 149 patients with atopic dermatitis and 194 with psoriasis. In a simultaneously conducted study once daily application of 0.1% halcinonide was compared to the cream base alone (placebo) in 48 patients with atopic dermatitis and 78 with psoriasis. Results show that a once daily regimen can be an effective treatment in both conditions, and can be recommended as a starting regimen in certain circumstances such as the treatment of young children or pregnant women, or where long-term treatment is likely. The three times daily regimen, however, was superior overall, and is still recommended as the treatment of choice, at least in severe psoriasis.

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The Philippines is an archipelago of about 7,100 tropical islands situated in the western Pacific Ocean 600 miles off the southeast corner of Asia. Located only about 15 ° north of the equator, the country has its share of tropical diseases, such as malaria, yaws, filariasis, schistosomiasis, typhoid fever, dysentery, intestinal parasitism, and mycotic infections. The beginnings of medical mycology in the Philippines may be traced to a number of publications by a singular group of American scientists, including STRONG, MUSGRAV~ and WADE, who worked in the Bureau of Science in Manila during the early years of the American regime in the Philippines, at the turn of the century. STRONC 1 in 1906, described what is probably the first recorded case of mycotic infection in the Philippines. The patient was a 35-year old Filipino woman with a skin lesion simulating a Delhi boil and exhibiting ttistoplasma-like organisms in tissue sections. These

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