The Apenninic fold-and-thrust belt in Italy represents one of several interconnected circum-Mediterranean orogens developed after the Late Cretaceous-early Cenozoic closure of Tethys and convergence between the European and African plates. The Geological Map of the Aventino River Valley, at 1:25,000 scale, provides original mapping of the outermost sector of Central Apennines in the Abruzzi region. Focusing on detailed mapping of the crosscutting relationships between the main regional thrust faults and tectonically driven stratigraphic unconformities, the map describes the complex structural and stratigraphic relationships between the Outer Abruzzi units (i.e. Porrara Unit), Apulia-Adriatic deformed units (i.e. Majella and Casoli Units), and the allochthonous Molise and Sicilide units. These tectono-stratigraphic relationships result from four main tectonic stages that occurred sequentially over a short time interval from late Messinian to early Pliocene.