Sickle-cell anemia (Sickle-cell anemia) is a disease characterized by the presence of abnormal red cells (sickle-shaped) that are removed from the circulation and destroyed by an inherited genetic disorder due to a mutation of the gene encoding the amino acid valine, transcribing an altered hemoglobin. The objective of the research is to verify the main means used for the laboratory diagnosis of sickle cell anemia and the carriers of these traits, as well as to perform an analysis of the literature related to the educational strategies on genetic counselingadded in the Unified Health System (SUS), especially in Attention Basic. An exploratory, descriptive research was carried out through a bibliographic review. The databases consulted were Virtual Health Library - VHL and SciELO - Scientific Electronic Library, where the existence of articles, dissertations, theses related to the subject were verified. It is observed that although there is a vast literature on Sickle Cell Anemia, there is little recent research in the databases used for this research related to the Diagnostics and educational strategies adopted in the Unified Health System (SUS), Anemia and genetic counseling.

The objective of this study was to analyze the epidemiological profile of tuberculosis cases between 2010 and 2018. It is an ecological study, of a descriptive nature and with a quantitative approach, using secondary data, in which an epidemiological research of cases of TB in the municipality of São Luís and in the state of Maranhão from 2010 to 2018. Data were collected on the DATASUS website, from SINAN. The variables analyzed were: year of diagnosis, notification state and municipality, age group, sex and education. An increasing trend was identified, with 2018 (n = 1,288) being the most incident year, the highest number of TB cases was reported in the state of Maranhão, followed by the years 2017 (n = 1,127) and 2016 (n = 1,092). Regarding the level of education, there is a predominance (19.1%) in people between the 5th and 8th grades of elementary school, followed by those between the 1st and 4th grades of Elementary School. With regard to TB cases by sex, the largest number of cases occurred in males (n = 6,133). Regarding the age group, a higher prevalence was observed between 20-39 years (n = 4,495), followed by the 40-59 age group (n = 2,689).

A espondilite anquilosante e o componente especializado da assistência farmacêutica do Piauí Anquilosante spondilite and the specialized component of pharmaceutical assistance of Piauí