Five new monoterpene indole alkaloids, naucleamides A-E (1-5), were isolated from the bark and wood of Nauclea latifolia, and the structures and relative stereochemistry were elucidated from the spectroscopic data. Naucleamide E (5) is a unique monoterpene indole alkaloid possessing a pentacyclic ring system with an amino acetal bridge.

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Methanol extracts of the seeds of Piper guineense (Piperaceae) were active against gold fish (Carassius auratus auratus L. Pisces Cyprinidae) monogenean parasites. The seed extract of P. guineense was administered at different concentrations (0.5-2.0 mg/L) under in vivo and in vitro conditions. There was a higher efficacy of the effects of the extracts against fish parasites under in vitro situations than under in vivo. Three major compounds (piperanine, N-isobutyl (E,E)-2,4 decadienamide and Deltaalpha,beta-dihydrowasanine) were identified from the seed extract of Piper guineense by LC-MS analysis.

A comparative study was carried out on the fatty acid content of palm oil samples from the red and yellow fruits of Dura and Tenera varieties of EIaeis guineensis in the dry (January) and wet (May) seasons. Significant differences in the fatty acid content of the oils from the two varieties were observed. The degree of total unsaturation of the oil samples varied, with oil from red fruits of Dura having the highest total unsaturated fatty acids.

Alkaloids Alkaloids U 0600Naucleamides A-E, New Monoterpene Indole Alkaloids from Nauclea latifolia.-Together with three known substances the novel title compounds such as (I)-(IV), named naucleamides A-E are isolated from the bark and wood of the title plant. -(SHIGEMORI, H.; KAGATA, T.; ISHIYAMA, H.; MORAH, F.; OHSAKI, A.; KOBAYASHI*, J.; Chem. Pharm. Bull. 51 (2003) 1, 58-61; Grad. Sch. Pharm. Sci., Hokkaido Univ., Sapporo 060, Japan; Eng.) -K. Schneider 23-198