The SES gradient in cardiovascular diseases reflects behavioral as well as physiological pathways and systemic inflammation seems to be involved. Low SES is associated with an increased exposure to adverse circumstances of life, which can trigger biological responses and result in an increased risk of cardiovascular diseases. Medical history taking in cardiology should focus on socio-structural exposures and thereby reflect the different meanings of education, occupation and income.

There is currently no clear evidence which intervention is the best to prevent antipsychotic-induced weight gain in patients with first episode of schizophrenia. Further trials of high methodological quality are necessary.

As a promising, patient-centred intervention which is compatible with the idea of recovery, Self-management support deserves closer attention.

Menschen aus niedrigeren sozialen Schichten haben ein erh?htes Depressionsrisiko und zeigen oft ung?nstigere Krankheitsverl?ufe als Menschen mit h?herem Sozialstatus. Bedeutsam sind psychosoziale Stressfaktoren, von denen sozial Benachteilige h?ufiger betroffen sind. Dazu geh?ren neben einschneidenden Lebensereignissen und andauernden Belastungen des t?glichen Lebens v.?a. psychosoziale Belastungen am Arbeitsplatz. Dieser Beitrag erl?utert die Bedeutung sozialer Faktoren f?r Entstehung und Verlauf von Depressionen.

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